Across TCGA pan-cancer cohorts, HSPE1P24 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of HSPE1P24’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where HSPE1P24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPE1P24 is over-expressed in tumor.
LUSC are the cancer types where HSPE1P24 tumor–normal differential expression is most reproducible.