HSPE1P22

Across TCGA pan-cancer cohorts, HSPE1P22 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated HSPE1P22 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher HSPE1P22 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated HSPE1P22 expression acts as an unfavorable survival marker, although some lineages such as LUSC and PAAD show a favorable association.

LUSC, PAAD, and THYM are the cancer types where HSPE1P22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.928	0.532	.002	72	view →
PAAD	OS	Tertile	All	0.705	0.276	.005	36	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	36	view →
BLCA	DFS	Tertile	IV	0.212	0.491	<.001	18	view →
PRAD	OS	Tertile	All	0.625	0.920	.001	12	view →
LIHC	OS	Tertile	III,IV	0.135	0.554	.014	9	view →
SARC	DFS	Tertile	All	0.369	0.616	.012	9	view →
KIRC	DFS	Tertile	IV	0.442	0.648	.046	6	view →
BRCA	DFS	Tertile	All	0.974	0.945	.034	6	view →
LGG	OS	Tertile	All	0.236	0.457	.013	6	view →
UCS	DFS	Tertile	All	0.711	0.218	.041	6	view →
ACC	OS	Tertile	IV	1.000	0.560	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

HSPE1P22–LUSC (DFS)

Open the LUSC breakdown →