HSPE1P21

Across TCGA pan-cancer cohorts, HSPE1P21 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated HSPE1P21 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher HSPE1P21 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPE1P21 expression acts as an unfavorable survival marker, although some lineages such as THYM show a favorable association.

LUAD, BLCA, and COAD are the cancer types where HSPE1P21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.392	0.788	<.001	123	view →
BLCA	DFS	Tertile	IV	0.165	0.485	.010	87	view →
COAD	DFS	Tertile	II,III,IV	0.429	0.790	<.001	54	view →
ACC	OS	Tertile	II,III,IV	0.551	0.879	.001	45	view →
LGG	OS	Tertile	All	0.790	0.907	.001	39	view →
STAD	OS	Quartile	II,III,IV	0.354	0.633	.005	36	view →
UVM	OS	Tertile	All	0.218	0.696	.014	36	view →
CESC	DFS	Tertile	All	0.699	0.841	.002	24	view →
KICH	DFS	Tertile	All	0.162	0.862	.014	15	view →
OV	OS	Quartile	III,IV	0.758	0.852	.007	14	view →
MESO	OS	Tertile	IV	0.318	0.629	.045	9	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

HSPE1P21–LUAD (DFS)

Open the LUAD breakdown →