HSPE1P20

Across TCGA pan-cancer cohorts, HSPE1P20 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated HSPE1P20 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher HSPE1P20 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPE1P20 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

SKCM, BLCA, and ESCA are the cancer types where HSPE1P20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	II,III,IV	0.119	0.405	<.001	66	view →
BLCA	DFS	Tertile	III,IV	0.157	0.473	.034	27	view →
ESCA	OS	Tertile	All	0.471	0.906	.031	18	view →
STAD	DFS	Tertile	III,IV	0.245	0.501	.026	13	view →
PAAD	OS	Tertile	All	0.331	0.601	.025	9	view →
SARC	DFS	Tertile	All	0.101	0.632	.011	9	view →
LUSC	DFS	Tertile	All	0.203	0.513	.020	9	view →
THCA	DFS	Tertile	II,III,IV	0.744	0.927	.010	9	view →
LAML	DFS	Tertile	All	1.000	0.534	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

HSPE1P20–SKCM (OS)

Open the SKCM breakdown →