HSPE1P2

Across TCGA pan-cancer cohorts, HSPE1P2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated HSPE1P2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher HSPE1P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPE1P2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUSC show a favorable association.

ACC, UVM, and ESCA are the cancer types where HSPE1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.184	0.751	<.001	77	view →
UVM	DFS	Median	All	0.425	0.743	<.001	70	view →
ESCA	OS	Tertile	III,IV	0.405	0.748	.003	56	view →
LUAD	OS	Quartile	III,IV	0.259	0.716	<.001	48	view →
KIRC	DFS	Tertile	II,III,IV	0.757	0.345	<.001	45	view →
PAAD	DFS	Tertile	All	0.356	0.575	<.001	45	view →
KIRP	DFS	Tertile	All	0.567	0.764	<.001	40	view →
LUSC	OS	Tertile	All	0.782	0.592	<.001	39	view →
READ	DFS	Median	All	0.896	0.740	.004	38	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	29	view →
LIHC	OS	Quartile	III,IV	0.315	0.638	.006	22	view →
LGG	DFS	Median	All	0.783	0.874	.001	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

HSPE1P2–ACC (DFS)

Open the ACC breakdown →