HSPE1P18

Across TCGA pan-cancer cohorts, HSPE1P18 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated HSPE1P18 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher HSPE1P18 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated HSPE1P18 expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

CESC, SKCM, and HNSC are the cancer types where HSPE1P18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.821	0.664	<.001	92	view →
SKCM	DFS	Tertile	All	0.701	0.559	<.001	87	view →
HNSC	DFS	Median	III,IV	0.675	0.515	.001	83	view →
LIHC	OS	Quartile	II,III,IV	0.334	0.692	<.001	65	view →
BRCA	OS	Median	II,III,IV	0.639	0.501	.006	46	view →
LAML	DFS	Tertile	All	0.273	0.500	.014	26	view →
UVM	DFS	Tertile	All	0.189	0.763	.004	18	view →
COAD	OS	Median	III,IV	0.338	0.696	.005	17	view →
SARC	OS	Quartile	All	0.934	0.793	<.001	15	view →
KIRC	DFS	Quartile	All	0.538	0.720	.007	13	view →
CHOL	DFS	Median	All	0.600	0.242	.026	12	view →
LUSC	DFS	Quartile	III,IV	0.738	0.386	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

HSPE1P18–CESC (DFS)

Open the CESC breakdown →