HSPE1P16

Across TCGA pan-cancer cohorts, HSPE1P16 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated HSPE1P16 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HSPE1P16 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPE1P16 expression acts as an unfavorable survival marker.

KIRC, BLCA, and ACC are the cancer types where HSPE1P16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.482	0.666	.005	87	view →
BLCA	OS	Tertile	III,IV	0.357	0.663	<.001	72	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	63	view →
THYM	DFS	Tertile	All	0.380	0.897	<.001	36	view →
PAAD	OS	Tertile	All	0.231	0.605	<.001	27	view →
PCPG	OS	Tertile	All	0.505	0.945	.001	27	view →
LUAD	OS	Tertile	All	0.371	0.798	<.001	24	view →
GBM	OS	Tertile	All	0.101	0.441	<.001	18	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
READ	DFS	Tertile	All	0.162	0.720	.019	18	view →
PRAD	OS	Tertile	All	0.623	0.977	<.001	18	view →
KIRP	OS	Tertile	All	0.707	0.893	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

HSPE1P16–KIRC (DFS)

Open the KIRC breakdown →