HSPE1P12

Across TCGA pan-cancer cohorts, HSPE1P12 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated HSPE1P12 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HSPE1P12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPE1P12 expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRC show a favorable association.

COAD, STAD, and LUAD are the cancer types where HSPE1P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.202	0.702	<.001	72	view →
STAD	OS	Tertile	IV	0.090	0.591	<.001	54	view →
LUAD	OS	Tertile	II,III,IV	0.330	0.753	.011	36	view →
THCA	DFS	Tertile	II,III,IV	0.145	0.794	.001	33	view →
ESCA	DFS	Tertile	III,IV	0.661	0.376	.032	18	view →
PRAD	OS	Tertile	All	0.929	0.995	.001	18	view →
KIRP	OS	Tertile	II,III,IV	0.216	0.771	.049	9	view →
KIRC	DFS	Tertile	II,III,IV	0.966	0.772	.028	6	view →
SARC	OS	Tertile	All	0.744	0.863	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

HSPE1P12–COAD (DFS)

Open the COAD breakdown →