HSPD1P4

Across TCGA pan-cancer cohorts, HSPD1P4 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated HSPD1P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HSPD1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPD1P4 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

KIRC, READ, and ACC are the cancer types where HSPD1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.748	0.859	<.001	76	view →
READ	OS	Median	III,IV	1.000	0.732	.006	47	view →
ACC	DFS	Median	All	0.233	0.646	<.001	46	view →
SKCM	OS	Quartile	II,III,IV	0.925	0.779	<.001	41	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	33	view →
LUAD	OS	Median	II,III,IV	0.639	0.840	<.001	32	view →
UCEC	DFS	Tertile	All	0.868	0.936	.001	32	view →
LUSC	OS	Tertile	All	0.498	0.346	.002	28	view →
LIHC	OS	Tertile	II,III,IV	0.488	0.760	.004	25	view →
THCA	DFS	Quartile	All	0.977	0.895	<.001	17	view →
GBM	DFS	Median	All	0.371	0.213	.020	16	view →
BRCA	DFS	Tertile	All	0.932	0.959	.029	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

HSPD1P4–KIRC (OS)

Open the KIRC breakdown →