HSPD1P13

Across TCGA pan-cancer cohorts, HSPD1P13 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of HSPD1P13’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where HSPD1P13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPD1P13 is over-expressed in tumor, although a few such as BRCA and ESCA show the opposite, repressed pattern.

KIRC, BRCA, and ESCA are the cancer types where HSPD1P13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPD1P13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.030	<.001	7	view →
BRCA	All	All	−0.027	.002	4	view →
ESCA	Female	All	−0.060	<.001	1	view →
LUAD	All	All	+0.009	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

HSPD1P13–KIRC

Open the KIRC breakdown →