HSPD1P11

Across TCGA pan-cancer cohorts, HSPD1P11 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated HSPD1P11 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher HSPD1P11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPD1P11 expression acts as an unfavorable survival marker, although some lineages such as LAML and UCS show a favorable association.

CESC, STAD, and UCEC are the cancer types where HSPD1P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Quartile	III,IV	0.466	0.845	.001	60	view →
STAD	OS	Tertile	II,III,IV	0.560	0.820	.001	57	view →
UCEC	OS	Median	All	0.889	0.953	<.001	54	view →
LAML	DFS	Median	All	0.694	0.443	<.001	54	view →
UCS	OS	Median	IV	0.752	0.404	.013	34	view →
LGG	DFS	Tertile	All	0.768	0.896	<.001	29	view →
DLBC	DFS	Tertile	II,III,IV	0.419	0.951	.005	21	view →
LIHC	DFS	Median	II,III,IV	0.232	0.395	.020	13	view →
BRCA	DFS	Tertile	III,IV	0.908	0.811	.007	10	view →
SARC	OS	Quartile	All	0.444	0.769	.008	10	view →
THCA	OS	Quartile	III,IV	0.713	1.000	.038	10	view →
KIRP	DFS	Tertile	All	0.419	0.688	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

HSPD1P11–CESC (DFS)

Open the CESC breakdown →