HSPBP1

Across TCGA patient cohorts, HSPBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,256 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPBP1-associated genes across cancer lineages are FBL, UBE2S, and CSE1L. Each is linked with HSPBP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSPBP1-to-partner and partner-to-HSPBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPBP1 versus FBL in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPBP1→partner) and Y-score (partner→HSPBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FBL →	+1.042	+0.341	<.001	<.001	3	8
HNSC	UBE2S →	+1.083	+0.417	<.001	<.001	3	8
LSCC	CSE1L →	+0.659	+0.222	<.001	<.001	3	7
LSCC	PDCD2L →	+0.614	+0.256	<.001	<.001	3	7
UCEC	BCL2L12 →	+0.903	+0.248	<.001	<.001	3	7
UCEC	TOMM40 →	+0.785	+0.180	.004	.008	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,256 associations by consensus.

HSPBP1 vs FBL — HNSC

Explore this scatter interactively →