HSPBAP1

Across TCGA pan-cancer cohorts, HSPBAP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated HSPBAP1 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher HSPBAP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPBAP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

UCEC, GBM, and LUAD are the cancer types where HSPBAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	II,III,IV	0.492	1.000	.018	12	view →
GBM	OS	Median	All	0.265	0.486	.012	6	view →
LUAD	DFS	Median	All	0.890	0.485	.015	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

HSPBAP1–UCEC (DFS)

Open the UCEC breakdown →