HSPBAP1

Across TCGA patient cohorts, HSPBAP1 mutation is significantly associated with the RNA expression of many other genes, with 830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPBAP1-associated genes across cancer lineages are NMD3P2, MIR3651, and OR7E46P. Each is linked with HSPBAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPBAP1-to-partner and partner-to-HSPBAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMD3P2 grouped by HSPBAP1-low versus HSPBAP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPBAP1→partner) and Y-score (partner→HSPBAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NMD3P2 →	+0.054	+5.010	<.001	.009	3	2
SKCM	MIR3651 →	+0.602	+3.881	<.001	.004	3	2
SKCM	OR7E46P →	+0.062	+4.368	<.001	<.001	3	2
SKCM	ARHGEF38-IT1 →	+0.144	+3.717	<.001	.005	3	2
UCEC	LINC01941 →	+0.029	+3.742	<.001	.001	3	2
CESC	MIR4314 →	+0.422	+5.306	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 830 associations by consensus.

NMD3P2 by HSPBAP1 expression — CESC

Explore this box plot interactively →