HSPB9

Across TCGA cell cohorts, HSPB9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,316 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HSPB9-associated GO terms across cancer lineages are Mitotic DNA integrity checkpoint signaling, Epigenetic regulation of gene expression, and Leading strand elongation. Each is linked with HSPB9 in more than 11 cancer types. Because this analysis shows association rather than direction, both HSPB9-to-partner and partner-to-HSPB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA integrity checkpoint signaling grouped by HSPB9-low versus HSPB9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB9→partner) and Y-score (partner→HSPB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic DNA integrity checkpoint signaling →	+0.084	+0.211	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Epigenetic regulation of gene expression →	+0.055	+0.152	.002	.008	3	12
LIVER	Leading strand elongation →	+0.166	+0.222	.001	.001	3	12
BONE	Mitotic DNA damage checkpoint signaling →	+0.082	+0.183	.001	<.001	3	11
SOFT_TISSUE	Regulation of RNA export from nucleus →	+0.127	+0.236	<.001	<.001	3	11
BONE	Regulation of calcium ion transport →	-0.101	-0.250	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,316 associations by consensus.

Mitotic DNA integrity checkpoint signaling by HSPB9 expression — BONE

Explore this box plot interactively →