HSPB7

Across TCGA patient cohorts, HSPB7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,608 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPB7-associated genes across cancer lineages are CHRDL1, SGCA, and AOC3. Each is linked with HSPB7 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSPB7-to-partner and partner-to-HSPB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB7 versus CHRDL1 in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB7→partner) and Y-score (partner→HSPB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHRDL1 →	+1.615	+0.827	<.001	<.001	3	9
HNSC	SGCA →	+1.638	+1.672	<.001	<.001	3	9
BRCA	AOC3 →	+1.243	+0.637	<.001	<.001	3	9
HNSC	NEXN →	+1.209	+1.530	<.001	<.001	3	9
UCEC	LMOD1 →	+1.875	+0.814	<.001	<.001	3	9
HNSC	DES →	+4.761	+1.648	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,608 associations by consensus.

HSPB7 vs CHRDL1 — UCEC

Explore this scatter interactively →