HSPB7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSPB7 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSPB7-associated genes across cancer lineages are FCN2. Each is linked with HSPB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPB7-to-partner and partner-to-HSPB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCN2 grouped by HSPB7-low versus HSPB7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB7→partner) and Y-score (partner→HSPB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFCN2 →+0.024+5.415.007.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

FCN2 by HSPB7 expression — LARGE_INTESTINE

Box plot of FCN2 in HSPB7-low vs HSPB7-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration