HSPB3

Across TCGA patient cohorts, HSPB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPB3-associated proteins across cancer lineages are VCL, PDLIM3, and RCN3. Each is linked with HSPB3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPB3-to-partner and partner-to-HSPB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB3 versus VCL in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB3→partner) and Y-score (partner→HSPB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VCL →	+0.662	+1.087	<.001	<.001	3	6
HNSC	PDLIM3 →	+0.977	+1.565	<.001	<.001	3	6
OV	RCN3 →	+0.563	+0.626	.002	.002	3	5
GBM	CDH13 →	+0.589	+0.684	<.001	<.001	3	5
UCEC	DAPK3 →	+0.475	+0.879	<.001	.001	3	5
UCEC	FILIP1L →	+0.789	+0.750	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,184 associations by consensus.

HSPB3 vs VCL — UCEC

Explore this scatter interactively →