HSPB3

Across TCGA patient cohorts, HSPB3 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible HSPB3-associated genes across cancer lineages are RNU4ATAC7P, RN7SKP135, and MTND1P35. Each is linked with HSPB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPB3-to-partner and partner-to-HSPB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4ATAC7P grouped by HSPB3-low versus HSPB3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB3→partner) and Y-score (partner→HSPB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU4ATAC7P →	+0.311	+7.741	<.001	.009	3	2
BRCA	RN7SKP135 →	+0.098	+7.731	<.001	.009	3	2
BRCA	MTND1P35 →	+0.094	+7.731	<.001	.009	3	2
BRCA	OR4M2 →	+0.044	+8.055	<.001	.007	3	1
COAD	RNU6-1167P →	+0.392	+7.741	<.001	.009	3	1
COAD	RNU6-591P →	+0.358	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

RNU4ATAC7P by HSPB3 expression — COAD

Explore this box plot interactively →