HSPB2

Across TCGA cell cohorts, HSPB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,054 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HSPB2-associated GO terms across cancer lineages are Regulation of macroautophagy, Potassium ion transmembrane transport, and Regulation of G1/S transition of mitotic cell cycle. Each is linked with HSPB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPB2-to-partner and partner-to-HSPB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by HSPB2-low versus HSPB2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB2→partner) and Y-score (partner→HSPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of macroautophagy →	+0.046	+0.993	<.001	.007	3	6
OVARY	Potassium ion transmembrane transport →	-0.046	-0.788	<.001	.004	2	7
LARGE_INTESTINE	Regulation of G1/S transition of mitotic cell cycle →	+0.044	+0.117	<.001	.004	3	5
OVARY	Potassium ion transport →	-0.049	-0.828	<.001	.002	3	5
BONE	Heparan sulfate proteoglycan catabolic process →	+0.225	+1.617	<.001	<.001	3	5
BONE	Regulation of Notch signaling pathway →	+0.057	+1.319	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,054 associations by consensus.

Regulation of macroautophagy by HSPB2 expression — OVARY

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