HSPA9

Across TCGA patient cohorts, HSPA9 protein abundance is significantly associated with the RNA expression of many other genes, with 15,916 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA9-associated genes across cancer lineages are JAM3, NEXN, and CYYR1. Each is linked with HSPA9 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSPA9-to-partner and partner-to-HSPA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA9 versus JAM3 in CCRCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA9→partner) and Y-score (partner→HSPA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	JAM3 →	-1.063	-0.451	<.001	<.001	3	9
COAD	NEXN →	-1.078	-0.301	<.001	.001	3	8
OV	CYYR1 →	-1.196	-0.470	<.001	<.001	3	8
UCEC	LDB2 →	-1.217	-0.391	<.001	<.001	3	8
OV	CXCL12 →	-1.358	-0.407	.002	<.001	3	7
OV	ACTA2 →	-1.808	-0.479	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,916 associations by consensus.

HSPA9 vs JAM3 — CCRCC

Explore this scatter interactively →