HSPA9

Across TCGA cell cohorts, HSPA9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,166 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible HSPA9-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Regulation of mitochondrial RNA catabolic process, and Positive regulation of mitochondrial RNA catabolic process. Each is linked with HSPA9 in more than 14 cancer types. Because this analysis shows association rather than direction, both HSPA9-to-partner and partner-to-HSPA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by HSPA9-low versus HSPA9-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA9→partner) and Y-score (partner→HSPA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of rRNA processing →	+0.130	+1.016	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mitochondrial RNA catabolic process →	+0.139	+0.848	<.001	.001	3	14
BLOOD_Myeloma	Positive regulation of mitochondrial RNA catabolic process →	+0.142	+0.983	<.001	.001	3	13
PANCREAS	rRNA metabolic process →	+0.080	+0.818	.004	.001	3	13
LARGE_INTESTINE	Maturation of SSU-rRNA →	+0.113	+0.898	<.001	<.001	3	12
SKIN	Mitochondrial tRNA wobble uridine modification →	+0.113	+0.509	<.001	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,166 associations by consensus.

Positive regulation of rRNA processing by HSPA9 expression — PANCREAS

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