heat shock protein family A (Hsp70) member 8 pseudogene 3Genealiases: []
Q-omics provides the consensus-scored HSPA8P3 profile across patient tissues and cancer cell-line models. HSPA8P3 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, HSPA8P3 is differentially expressed in 11, with the highest sampling consensus in STAD. Additionally, HSPA8P3 RNA expression shows 14,830 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight LIHC, STAD, and LSCC as cancer lineages where HSPA8P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPA8P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPA8P3 survival associations across molecular data types. HSPA8P3 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPA8P3 RNA expression–survival associations across cancer types. High HSPA8P3 expression shows unfavorable associations in LIHC, SKCM, ACC and UCEC, but favorable associations in READ and STAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for HSPA8P3 RNA expression.
This table summarizes HSPA8P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for HSPA8P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPA8P3 shows lower tumor expression in THCA and higher tumor expression in STAD, HNSC, BLCA, BRCA and COAD. The STAD box plot shows higher HSPA8P3 RNA expression in tumor versus normal tissue (log2 FC = +0.315, t-test p = .001).
This table shows molecular features associated with HSPA8P3 in patient tissues and cancer cell lines. In patient samples, HSPA8P3 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
