Across TCGA pan-cancer cohorts, HSPA8P19 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HSPA8P19’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where HSPA8P19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPA8P19 is over-expressed in tumor.
KIRC, LUSC, and BRCA are the cancer types where HSPA8P19 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPA8P19 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.