HSPA8P1

Across TCGA pan-cancer cohorts, HSPA8P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of HSPA8P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HSPA8P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPA8P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, LIHC, and LUAD are the cancer types where HSPA8P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPA8P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.729	<.001	10	view →
LIHC	All	All	+0.231	<.001	5	view →
LUAD	All	All	+0.299	.001	4	view →
BRCA	All	All	+0.206	<.001	4	view →
CHOL	All	All	+0.352	.002	3	view →
PRAD	All	All	+0.241	.005	2	view →
THCA	All	All	−0.213	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

HSPA8P1–COAD

Open the COAD breakdown →