HSPA8

Across TCGA patient cohorts, HSPA8 protein abundance is significantly associated with the RNA expression of many other genes, with 19,552 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPA8-associated genes across cancer lineages are MTFR2, HSPA4, and UBE2T. Each is linked with HSPA8 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPA8-to-partner and partner-to-HSPA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA8 versus MTFR2 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA8→partner) and Y-score (partner→HSPA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTFR2 →	+0.948	+0.257	<.001	.001	3	6
UCEC	HSPA4 →	+0.570	+0.135	<.001	<.001	3	6
LSCC	UBE2T →	+0.858	+0.147	<.001	<.001	3	6
UCEC	CENPM →	+1.090	+0.129	<.001	<.001	3	5
COAD	NCAPG →	+0.858	+0.145	<.001	.001	3	5
OV	TNS2 →	-1.029	-0.212	.008	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,552 associations by consensus.

HSPA8 vs MTFR2 — OV

Explore this scatter interactively →