HSPA8

Across TCGA cell cohorts, HSPA8 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSPA8-associated genes across cancer lineages are NAA38, PROKR2, and KIAA1210. Each is linked with HSPA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA8-to-partner and partner-to-HSPA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAA38 grouped by HSPA8-low versus HSPA8-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA8→partner) and Y-score (partner→HSPA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NAA38 →	+1.159	+3.212	<.001	.006	3	2
OESOPHAGUS	PROKR2 →	+0.068	+4.017	<.001	.007	3	1
OESOPHAGUS	KIAA1210 →	+0.028	+4.017	<.001	.007	3	1
CNS	PRAMEF26 →	+0.270	+5.754	.005	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.576	+3.299	.004	.004	3	1
LARGE_INTESTINE	PSMD14 →	+0.317	+3.137	.009	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

NAA38 by HSPA8 expression — LARGE_INTESTINE

Explore this box plot interactively →