HSPA4

Across TCGA patient cohorts, HSPA4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,257 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HSPA4-associated genes across cancer lineages are PHAX, HINT1, and HSPA9. Each is linked with HSPA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSPA4-to-partner and partner-to-HSPA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA4 versus PHAX in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4→partner) and Y-score (partner→HSPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PHAX →	+0.639	+0.162	.001	<.001	3	8
OV	HINT1 →	+0.694	+0.334	<.001	<.001	3	8
OV	HSPA9 →	+0.593	+0.366	<.001	<.001	3	7
UCEC	IK →	+0.559	+0.112	<.001	.001	3	7
OV	PPP2CA →	+0.489	+0.325	<.001	<.001	3	7
OV	ETF1 →	+0.563	+0.281	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,257 associations by consensus.

HSPA4 vs PHAX — UCEC

Explore this scatter interactively →