HSPA4

Across TCGA cell cohorts, HSPA4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSPA4-associated genes across cancer lineages are OR9G1 and OR56A5. Each is linked with HSPA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA4-to-partner and partner-to-HSPA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9G1 grouped by HSPA4-low versus HSPA4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4→partner) and Y-score (partner→HSPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR9G1 →	+0.283	+4.874	<.001	.002	3	1
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.045	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR9G1 by HSPA4 expression — BLOOD_Leukemia

Explore this box plot interactively →