HSPA2

Across TCGA patient cohorts, HSPA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPA2-associated proteins across cancer lineages are LAMB1, DDX18, and AHNAK2_S497. Each is linked with HSPA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HSPA2-to-partner and partner-to-HSPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA2 versus LAMB1 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA2→partner) and Y-score (partner→HSPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LAMB1 →	+0.407	+0.901	.005	.001	3	5
BRCA	DDX18 →	-0.277	-0.834	<.001	.002	3	4
GBM	AHNAK2_S497 →	+1.507	+1.422	<.001	.001	3	4
OV	DYNC1LI2 →	+0.286	+1.057	.006	.002	3	4
COAD	GPATCH4 →	-0.456	-0.726	.002	.002	3	4
HNSC	TRRAP →	-0.188	-1.046	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,742 associations by consensus.

HSPA2 vs LAMB1 — OV

Explore this scatter interactively →