HSPA2

Across TCGA patient cohorts, HSPA2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,931 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HSPA2-associated genes across cancer lineages are PPP1R36, PPP1R14A, and PLEKHG3. Each is linked with HSPA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPA2-to-partner and partner-to-HSPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA2 versus PPP1R36 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA2→partner) and Y-score (partner→HSPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R36 →	+0.813	+0.834	<.001	<.001	3	6
GBM	PPP1R14A →	+1.167	+0.598	.003	.001	3	6
GBM	PLEKHG3 →	+0.850	+0.708	<.001	<.001	3	5
UCEC	PRKCD →	-0.696	-0.647	<.001	<.001	3	5
PDAC	FHL5 →	+0.760	+0.242	<.001	<.001	3	5
BRCA	BCAS1 →	+2.049	+0.831	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,931 associations by consensus.

HSPA2 vs PPP1R36 — BRCA

Explore this scatter interactively →