Across TCGA patient cohorts, HSPA1L protein abundance is significantly associated with the RNA expression of many other genes, with 4,541 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HSPA1L-associated genes across cancer lineages are RCVRN, RNU4-28P, and LINC02664. Each is linked with HSPA1L in more than 2 cancer types. Because this analysis shows association rather than direction, both HSPA1L-to-partner and partner-to-HSPA1L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1L→partner) and Y-score (partner→HSPA1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCVRN →	-0.278	-0.726	.001	.002	3	2
LUAD	RNU4-28P →	-0.479	-0.212	<.001	<.001	3	2
PDAC	LINC02664 →	-0.240	-0.179	.005	.003	3	2
GBM	PXMP4 →	-0.427	-0.136	<.001	.006	3	2
UCEC	ATP8B4 →	+0.515	+0.255	.002	<.001	3	2
GBM	FCGRT →	+0.366	+0.184	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,541 associations by consensus.

Exploration

HSPA1L survival (RNA) · tumor vs normal (RNA) · all HSPA1L data types