HSPA1L

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSPA1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,187 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSPA1L-associated GO terms across cancer lineages are Positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway, Regulation of protein folding, and Positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Each is linked with HSPA1L in more than 9 cancer types. Because this analysis shows association rather than direction, both HSPA1L-to-partner and partner-to-HSPA1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1L→partner) and Y-score (partner→HSPA1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaPositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway →+0.163+0.577<.001<.001310
LUNG_SCLCRegulation of protein folding →+0.085+0.681.008<.00139
BLOOD_LymphomaPositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →+0.172+0.591<.001<.00139
CNSNegative regulation of inclusion body assembly →+0.170+0.419<.001<.00139
OESOPHAGUSMacroautophagy →+0.055+0.370<.001.00338
PANCREASProcess utilizing autophagic mechanism →+0.056+0.439.004.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,187 associations by consensus.

Exploration