Across TCGA cell cohorts, HSPA1L mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSPA1L-associated genes across cancer lineages are NSC-207895, kb NB 142-70, and RU-SKI 43. Each is linked with HSPA1L in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA1L-to-partner and partner-to-HSPA1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1L→partner) and Y-score (partner→HSPA1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NSC-207895 →	+0.637	+2.914	.001	.012	3	1
LARGE_INTESTINE	kb NB 142-70 →	+0.458	+2.874	.041	.021	3	1
BLOOD_Leukemia	RU-SKI 43 →	+0.377	+2.845	.009	.028	3	1
LARGE_INTESTINE	Sabutoclax →	+0.501	+2.991	.011	.018	2	1
LARGE_INTESTINE	Quizartinib →	+0.439	+2.874	.003	.021	1	2
LARGE_INTESTINE	Ara-G →	+0.186	+2.944	.019	.018	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

HSPA1L survival (RNA) · tumor vs normal (RNA) · all HSPA1L data types