Across TCGA patient cohorts, HSPA1B mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. CESC shows the largest number of these associations.

The most reproducible HSPA1B-associated genes across cancer lineages are MIR8070, ZNF736P7Y, and RN7SL288P. Each is linked with HSPA1B in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA1B-to-partner and partner-to-HSPA1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1B→partner) and Y-score (partner→HSPA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR8070 →	+0.794	+4.208	<.001	.009	3	2
COAD	ZNF736P7Y →	+0.155	+6.251	<.001	.001	3	2
CESC	RN7SL288P →	+0.106	+3.839	<.001	.004	3	1
CESC	CSAG4 →	+1.185	+4.590	<.001	<.001	3	1
CESC	RN7SL111P →	+0.179	+3.376	<.001	.007	3	1
CESC	PMPCAP1 →	+0.544	+4.119	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Exploration

HSPA1B survival (RNA) · tumor vs normal (RNA) · all HSPA1B data types