Across TCGA cell cohorts, HSPA1B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HSPA1B-associated genes across cancer lineages are OR10H5, C16orf82, and DCD. Each is linked with HSPA1B in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA1B-to-partner and partner-to-HSPA1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1B→partner) and Y-score (partner→HSPA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10H5 →	+0.012	+4.977	<.001	.007	3	1
SKIN	C16orf82 →	+0.016	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	DCD →	+0.045	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

HSPA1B survival (RNA) · tumor vs normal (RNA) · all HSPA1B data types