Across TCGA patient cohorts, HSPA1A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,617 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPA1A-associated proteins across cancer lineages are PTGES3_S85, HNRNPA0_S84, and HNRNPH1_S23. Each is linked with HSPA1A in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPA1A-to-partner and partner-to-HSPA1A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1A→partner) and Y-score (partner→HSPA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTGES3_S85 →	+0.839	+1.181	<.001	<.001	3	7
PDAC	HNRNPA0_S84 →	+1.186	+0.939	<.001	<.001	3	6
PDAC	HNRNPH1_S23 →	+0.799	+1.225	<.001	<.001	3	6
LSCC	PPP1R12A_S995 →	+0.599	+0.940	<.001	.001	3	6
LSCC	CEP250_S1295 →	+0.603	+0.935	<.001	<.001	3	5
GBM	CSDE1_S584 →	+0.861	+1.452	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,617 associations by consensus.

Exploration

HSPA1A survival (RNA) · tumor vs normal (RNA) · all HSPA1A data types