Across TCGA patient cohorts, HSPA1A mutation is significantly associated with the RNA expression of many other genes, with 666 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPA1A-associated genes across cancer lineages are RNU6-791P, LINC01751, and MIR4652. Each is linked with HSPA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA1A-to-partner and partner-to-HSPA1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1A→partner) and Y-score (partner→HSPA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-791P →	+0.227	+5.252	<.001	.002	3	2
BLCA	LINC01751 →	+0.020	+5.033	<.001	.003	3	2
BLCA	MIR4652 →	+0.359	+4.376	.007	.002	3	2
BLCA	OR8D2 →	+0.030	+5.033	<.001	.003	3	2
BLCA	TEX33 →	+0.086	+3.758	<.001	.008	3	2
BLCA	MIR515-2 →	+0.596	+5.229	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 666 associations by consensus.

Exploration

HSPA1A survival (RNA) · tumor vs normal (RNA) · all HSPA1A data types