HSPA1A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSPA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,208 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSPA1A-associated GO terms across cancer lineages are Heat acclimation, Cellular heat acclimation, and Positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Each is linked with HSPA1A in more than 18 cancer types. Because this analysis shows association rather than direction, both HSPA1A-to-partner and partner-to-HSPA1A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1A→partner) and Y-score (partner→HSPA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaHeat acclimation →+0.279+4.166<.001<.001319
BLOOD_LymphomaCellular heat acclimation →+0.279+4.166<.001<.001319
LARGE_INTESTINEPositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →+0.236+2.995<.001<.001317
BONENegative regulation of inclusion body assembly →+0.232+1.587<.001<.001317
LARGE_INTESTINEPositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway →+0.225+2.995<.001<.001317
PANCREASRegulation of inclusion body assembly →+0.110+1.306<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,208 associations by consensus.

Exploration