Across TCGA cell cohorts, HSPA1A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HSPA1A-associated genes across cancer lineages are AQP12A and GYPB. Each is linked with HSPA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA1A-to-partner and partner-to-HSPA1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA1A→partner) and Y-score (partner→HSPA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	AQP12A →	+0.040	+4.981	<.001	.008	3	1
CNS	GYPB →	+0.134	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

HSPA1A survival (RNA) · tumor vs normal (RNA) · all HSPA1A data types