HSPA13

Across TCGA patient cohorts, HSPA13 mutation is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPA13-associated genes across cancer lineages are MIR599, AQP7P4, and RNA5SP299. Each is linked with HSPA13 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSPA13-to-partner and partner-to-HSPA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR599 grouped by HSPA13-low versus HSPA13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA13→partner) and Y-score (partner→HSPA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR599 →	+0.339	+5.144	<.001	.003	3	3
CESC	AQP7P4 →	+0.064	+4.539	<.001	.008	3	2
CESC	RNA5SP299 →	+0.246	+4.812	<.001	.006	3	2
CESC	CCL27 →	+0.065	+4.812	<.001	.006	3	2
SKCM	TAF1C →	+0.792	+3.208	<.001	.009	3	2
UCEC	C19orf54 →	+0.504	+4.191	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

MIR599 by HSPA13 expression — CESC

Explore this box plot interactively →