HSPA13

Across TCGA cell cohorts, HSPA13 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSPA13-associated genes across cancer lineages are ZSWIM2, GSTA3, and AGTR2. Each is linked with HSPA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA13-to-partner and partner-to-HSPA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSWIM2 grouped by HSPA13-low versus HSPA13-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA13→partner) and Y-score (partner→HSPA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZSWIM2 →	+0.035	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	GSTA3 →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	AGTR2 →	+0.023	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OTOL1 →	+0.012	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR5P2 →	+0.028	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	SLC22A10 →	+0.431	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

ZSWIM2 by HSPA13 expression — BLOOD_Lymphoma

Explore this box plot interactively →