HSPA12B

Across TCGA patient cohorts, HSPA12B protein abundance is significantly associated with the RNA expression of many other genes, with 20,090 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSPA12B-associated genes across cancer lineages are CCM2L, TEK, and STARD8. Each is linked with HSPA12B in more than 9 cancer types. Because this analysis shows association rather than direction, both HSPA12B-to-partner and partner-to-HSPA12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA12B versus CCM2L in CCRCC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA12B→partner) and Y-score (partner→HSPA12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CCM2L →	+0.978	+0.522	<.001	<.001	3	10
CCRCC	TEK →	+1.365	+0.589	<.001	<.001	3	10
HNSC	STARD8 →	+0.788	+0.475	<.001	<.001	3	10
CCRCC	RAMP2 →	+1.058	+0.533	<.001	<.001	3	10
CCRCC	PTH1R →	+1.162	+0.376	<.001	<.001	3	10
CCRCC	CLEC14A →	+1.245	+0.506	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,090 associations by consensus.

HSPA12B vs CCM2L — CCRCC

Explore this scatter interactively →