HSPA12B

Across TCGA patient cohorts, HSPA12B mutation is significantly associated with the RNA expression of many other genes, with 1,951 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPA12B-associated genes across cancer lineages are KRT8P47, MIR3619, and RNA5SP73. Each is linked with HSPA12B in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA12B-to-partner and partner-to-HSPA12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT8P47 grouped by HSPA12B-low versus HSPA12B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA12B→partner) and Y-score (partner→HSPA12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	KRT8P47 →	+0.041	+5.355	<.001	.005	3	2
COAD	MIR3619 →	+0.729	+4.542	.002	.001	3	2
LUSC	RNA5SP73 →	+0.545	+4.652	<.001	.004	3	2
LUSC	RNU6-528P →	+0.418	+4.882	<.001	.005	3	2
UCEC	PPIL2 →	+0.340	+2.823	.003	.001	3	2
UCEC	RHBDD3 →	+0.415	+1.925	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,951 associations by consensus.

KRT8P47 by HSPA12B expression — LIHC

Explore this box plot interactively →