HSP90B1

Across TCGA patient cohorts, HSP90B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,776 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSP90B1-associated proteins across cancer lineages are CKAP4, FNDC3B, and EIF4B_S93. Each is linked with HSP90B1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSP90B1-to-partner and partner-to-HSP90B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSP90B1 versus CKAP4 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90B1→partner) and Y-score (partner→HSP90B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CKAP4 →	+0.536	+0.552	<.001	<.001	3	7
GBM	FNDC3B →	+0.486	+0.477	<.001	<.001	3	7
LUAD	EIF4B_S93 →	+0.631	+0.382	.001	.005	3	6
LUAD	LARP4_S583 →	+0.511	+0.667	<.001	<.001	3	6
GBM	PLOD1 →	+0.558	+0.330	<.001	<.001	3	6
CCRCC	PLOD2 →	+0.889	+0.486	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,776 associations by consensus.

HSP90B1 vs CKAP4 — BRCA

Explore this scatter interactively →