HSP90AB6P

Across TCGA pan-cancer cohorts, HSP90AB6P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated HSP90AB6P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher HSP90AB6P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSP90AB6P expression acts as an unfavorable survival marker, although some lineages such as SKCM and ACC show a favorable association.

LIHC, CHOL, and SKCM are the cancer types where HSP90AB6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.341	0.566	<.001	72	view →
CHOL	OS	Tertile	All	0.019	0.800	<.001	54	view →
SKCM	OS	Quartile	All	0.892	0.759	<.001	30	view →
ACC	DFS	Tertile	IV	0.592	0.241	.020	16	view →
LUAD	DFS	Median	IV	0.829	0.349	.024	12	view →
THYM	DFS	Tertile	All	0.968	0.828	.021	12	view →
CESC	OS	Tertile	III,IV	0.212	0.489	.043	12	view →
HNSC	DFS	Quartile	III,IV	0.670	0.540	.016	11	view →
KIRC	DFS	Tertile	IV	0.482	0.671	.027	10	view →
PAAD	OS	Tertile	II,III,IV	0.472	0.609	.030	9	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
OV	OS	Tertile	IV	0.527	0.288	.017	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

HSP90AB6P–LIHC (DFS)

Open the LIHC breakdown →