HSP90AB4P

Across TCGA patient cohorts, HSP90AB4P RNA expression is significantly associated with the protein abundance of many other proteins, with 8,913 significant associations in total. OV shows the largest number of these associations.

The most reproducible HSP90AB4P-associated proteins across cancer lineages are UBE2J1_S251, TP53BP1_S1114, and USP8. Each is linked with HSP90AB4P in more than 3 cancer types. Because this analysis shows association rather than direction, both HSP90AB4P-to-partner and partner-to-HSP90AB4P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSP90AB4P versus UBE2J1_S251 in UCEC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB4P→partner) and Y-score (partner→HSP90AB4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2J1_S251 →	-1.307	-0.595	<.001	<.001	3	4
OV	TP53BP1_S1114 →	+0.637	+1.088	<.001	<.001	3	3
LUAD	USP8 →	+0.231	+0.435	<.001	.001	3	3
LUAD	VPS54_S35 →	-0.527	-0.396	<.001	.001	3	3
LUAD	ZNF592_S348 →	+0.440	+0.549	.001	<.001	3	3
PDAC	SSH1_S441 →	+0.976	+0.405	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,913 associations by consensus.

HSP90AB4P vs UBE2J1_S251 — UCEC

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