HSP90AB4P

Across TCGA cell cohorts, HSP90AB4P protein abundance is significantly associated with the RNA expression of many other genes, with 1,336 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible HSP90AB4P-associated genes across cancer lineages are PSMG1, DNAJC19, and CNIH1. Each is linked with HSP90AB4P in more than 4 cancer types. Because this analysis shows association rather than direction, both HSP90AB4P-to-partner and partner-to-HSP90AB4P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSP90AB4P versus PSMG1 in BLOOD_Myeloma, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB4P→partner) and Y-score (partner→HSP90AB4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PSMG1 →	+0.944	+1.001	.001	.002	3	5
PANCREAS	DNAJC19 →	+0.847	+0.698	.007	.005	3	5
BLOOD_Leukemia	CNIH1 →	+0.621	+0.694	.005	.003	3	5
OESOPHAGUS	H2BC12 →	-1.554	-1.118	.005	.002	3	4
BLOOD_Myeloma	MRPS15 →	+0.887	+1.097	.002	.008	3	4
BLOOD_Myeloma	MRPS9 →	+0.695	+0.799	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,336 associations by consensus.

HSP90AB4P vs PSMG1 — BLOOD_Myeloma

Explore this scatter interactively →