HSP90AB3P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSP90AB3P mutation is significantly associated with the RNA expression of many other genes, with 2,117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSP90AB3P-associated genes across cancer lineages are LINC00440, MTCO1P1, and RNU4-89P. Each is linked with HSP90AB3P in more than 2 cancer types. Because this analysis shows association rather than direction, both HSP90AB3P-to-partner and partner-to-HSP90AB3P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB3P→partner) and Y-score (partner→HSP90AB3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCLINC00440 →+0.527+3.832<.001.00433
HNSCMTCO1P1 →+0.025+4.526<.001.00732
UCECRNU4-89P →+0.445+2.028.007.00632
UCECFRG1HP →+0.717+3.606<.001.00132
CESCRNU6-517P →+0.527+5.786<.001<.00132
CESCRNA5SP241 →+0.282+4.969<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,117 associations by consensus.

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