Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, HSP90AB3P mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible HSP90AB3P-associated genes across cancer lineages are eIF4G, INPP4B, and MEK1. Each is linked with HSP90AB3P in more than 1 cancer types. Because this analysis shows association rather than direction, both HSP90AB3P-to-partner and partner-to-HSP90AB3P results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (HSP90AB3P→partner) and Y-score (partner→HSP90AB3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.